![]() Quiescent tissue stem cells evade immune surveillance. S., Sachidanandam, R., Baccarini, A., Merad, M.et al. A., Alibo, E., Sweeney, R., Dhainaut, M., Kobayashi, K. Finally, protein homeostasis (proteostasis) is emerging as an important regulator of adult stem cells, not only controlling energy metabolism but also the abundance of proteins that act as regulators of the quiescence-to-activation transition.Īgudo, J., Park, E. Post-transcriptional regulation of gene expression also plays an important role in the quiescent-to-activation transition this is a process that could be facilitated and/or controlled by phase-separation mechanisms. In addition, key stem cell activation factors, such as MyoD1 and Ascl1, are potent reprogramming factors that harbour the ability to open closed chromatin. Important changes in chromatin accessibility have also been reported between quiescent and active stem cells. Intron-retained transcripts are accumulated in quiescent stem cells and are processed upon stem cell activation. Some of the processes that contribute to the activation of quiescent stem cells are depicted. Additionally, 23 scholars received 4 badges this academic year. The program will continue to implement innovative mechanisms to keep the student scholars connected and engaged in STEM identity development.The features and molecular regulation of adult stem cell quiescence and activation. Yechan Kim, UCD, 6 badges Sidi Diawo, UofM, 6 badges Anthony Dagher, UCD, 5 badges Marilyn Ho, IUPUI, 5 badges and Anna Osborne, UCD, 5 badges. The Urban STEM Collaboratory is delighted to recognize those students from each campus that earned the most badges during the 2019-2020 academic year: “With the pandemic, suffice it to say that face-to-face engagement has some new constraints therefore, student engagement and community building through innovative online tools, such as those offered by the CN, have never been more relevant.” “We see these engagement indicators increasing with students and faculty utilizing CN tools as we enter a ‘new normal’ for learning and student engagement in the era of COVID-19,” stated David Russomanno, Dean of the School of Engineering and Technology at IUPUI. ![]() Of particular note, 32 students earned the Learning Continuity badge through sharing helpful online learning and teaching tips in the face of the coronavirus pandemic. In addition to the campus competition, during the first academic year of the program, 104 STEM Collaboratory Participant badges were awarded. However, if the competition criteria was modified to be based on the average number of reflections, post ratings, or Anar Seeds per student, the UofM would have been the undisputable winner. In short, each campus distinguished itself in student engagement via the CN. UCD placed second with 7.7 posts/student. ![]() Based on the average number of posts created by each student scholar, IUPUI won the campus competition with an average of 8.2 posts/student. In the 2019-2020 academic year, a total of 508 posts were created by students in the Urban STEM Collaboratory Network on CN. The CN’s Anar Seeds engine automatically tracks users’ participation, allowing the program to assess members’ engagement, as well as organize cross-campus activities, including competitions. Scholars also document their STEM experiences on their lifelong CN ePortfolio to earn program badges certifying various activities and accomplishments, such as Research Scholar, Diversity Scholar, Industry Intern, STEM Tutor, Peer Led Team Leader, and several other badges. ![]() Student scholars share aspects of their academic life, challenges, interests, and learning resources with each other through a posting feature via CN. This project investigates and implements mechanisms for supporting a diverse cohort of students in an urban context in their development of a STEM identity.ĬourseNetworking (CN), an academic social networking platform developed by members of the IUPUI CyberLab, has been adopted by the Urban STEM Collaboratory to connect student scholars within and across the three campuses. The Urban STEM Collaboratory is a NSF-supported collaborative project led by the University of Memphis (UofM), the University of Colorado at Denver (UCD), and Indiana University-Purdue University Indianapolis (IUPUI) that provides scholarships and a variety of academic support to financially disadvantaged student scholars pursuing baccalaureate degrees in engineering or mathematics.
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